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What we can do is compare their proposed mechanisms, the type of injury they are most associated with in animal research, and their practical characteristics

S4 show that both GLP-1RA and SGLT-2 inhibitors were associated with a lower risk for nonfatal MI as compared with placebo (9% and 13%, respectively), or with DPP-4 inhibitors (10% and 14%, respectively), which was significant for the comparison between SGLT-2 and DPP-4 inhibitors only

Analyses of the active-treatment period include patients who had either completed 52 weeks from the start of IMCIVREE treatment or discontinued the trial early at the time of the prespecified data cutoff

OBrien K et al, Reasons for wanting to lose weight: different strokes for different folks

Neurology 44: 10901096