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The drug essentially recalibrates how your brain interprets hunger and fullness cues

Given that GLP-1-RAs alter gut motility and secretion, and that the gut microbiota can influence host eating behavior, including food preferences, it is plausible that these drugs indirectly influence taste perception by modulating microbial composition and the subsequent production of metabolites that can signal to the brain, potentially via vagal afferents or systemic circulation

V., Cella, M., et al

But overall, the relative risk ratios for nonfatal stroke and fatal/nonfatal stroke were not statistically significant. Current guidelines from the ADA and American Stroke Association recommend GLP-1 RAs for secondary ischemic stroke prevention

Prescribers typically start with a lower dose and gradually increase it to an effective level to minimize potential side effects