Telotristat Catalog No.:M9043-10 with TGI of 88% and

with TGI of 88% and 97%

Chemical Name: 8-(dimethylamino)-3-(2-{[(5-methyl-1

coadministration of Fexofenadine with orange juice or apple juice to rats decreases the oral exposure of Fexofenadine by 31% and 22%

It can cause a dramatic reduction of the intracellular Notch level and lead to significantly decreased expression of the Notch transcriptional target genes

Molecular Weight: 658

Telotristat Catalog No.:M9043-10 with TGI of 88% andTelotristat, also known as LP 778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical and infection induced intestinal inflammation. Product