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Unlike the stable heteropentameric retromer complex in yeast, the SNX-BAR heterodimers SNX1/2SNX5/6 in animals can assemble into functionally distinct endosomal sorting complexes (ESCPE-1) that operate independently of the retromer core 29

Each hydrogen bond (H bond) requires a hydrogen-bond donor and a hydrogen-bond acceptor, as shown in Figure 2-13

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