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About NeuroBo Pharmaceuticals NeuroBo Pharmaceuticals, Inc

TMAO, trimethylamine-N-oxide

235 In addition to MCT1, CD8 T cells also increase lactate uptake by upregulating MCT11, which accelerates the exhaustion of effector T cells

PMID: 39591965 Cell Metab 2019 Jul 2;30(1):157-173.e7 PMID: 31155494 Autophagy XIAP-ULK1-Mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease

While some trials have reported modest cognitive or motor benefits, others including recent phase 3 trials have shown no significant effect on disease progression