NMS-1286937 Catalog No.:M9125-2 cell-permeable γ-secretase inhibitor (IC50= 0

cell-permeable γ-secretase inhibitor (IC50= 0

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51

Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines

Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women

Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4

NMS-1286937 Catalog No.:M9125-2 cell-permeable γ-secretase inhibitor (IC50= 0Onvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1