Lodoxamide - CAS# 53882-12-5 size:2mg solid Solubility: DMSO up to 20
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Lodoxamide - CAS# 53882-12-5 size:2mg solid Solubility: DMSO up to 20Lodoxamide, CAS No. 53882 12 5, is a potent agonist of GPR35 with an EC50 value of 1. 61 nM in a arrestin 2 interaction assay using CHO K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48 80 (Item No. 22173), anti IgE, or A23187 (Item No. 11016) in isolated rat peritoneal mast cells (IC50s = 0. 1 50 M) and inhibits A23187 induced calcium influx in mast cells. It reduces antigen induced histamine release from
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