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UNC0224 - CAS# 1197196-48-7 Size:Solid 2 mg it shares a polycyclic intercalating

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UNC0224 - CAS# 1197196-48-7 Size:Solid 2 mg it shares a polycyclic intercalatingNC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM. 4 Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM. Product information CAS Number: 1197196 48 7 Molecular Weight: 485. 67 Formula: C26H43N7O2 Synonym: UNC 0224 UNC 0224 Chemical Name: 7 [3 (dimethylamino)propoxy] 6 methoxy 2 (4 methyl 1,4 diazepan 1 yl) N (1 methylpiperidin 4 yl)quinazolin 4 amine Smiles:

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Description

it shares a polycyclic intercalating moiety and charged side chains that stabilize DNA binding

Formula: C21H23Cl2N5O2S

Berzosertib (VE822) was discontinued

ZSTK474 shows potent antiproliferative activity against a panel of 39 human cancer cell lines with mean GI50 of 0

InChi: InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-22-11-13-26(15-19-8-3-2-4-9-19)17-21(22)23(29)27-14-12-25-24(27)28/h2-10H

UNC0224 - CAS# 1197196-48-7 Size:Solid 2 mg it shares a polycyclic intercalatingNC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM. 4 Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM. Product information CAS Number: 1197196 48 7 Molecular Weight: 485. 67 Formula: C26H43N7O2 Synonym: UNC 0224 UNC 0224 Chemical Name: 7 [3 (dimethylamino)propoxy] 6 methoxy 2 (4 methyl 1,4 diazepan 1 yl) N (1 methylpiperidin 4 yl)quinazolin 4 amine Smiles:

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