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PHA-665752 Catalog No.:M7762-10 1'E)-(2-methoxy-1

PHA-665752 Catalog No.:M7762-10 1'E)-(2-methoxy-1

Name: PHA-665752 Catalog No.:M7762-10 1'E)-(2-methoxy-1
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SKU: 88924352436
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PHA-665752 Catalog No.:M7762-10 1'E)-(2-methoxy-1PHA665752 is a potent and selective inhibitor of c Met HGF SF (IC50 values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk 1, c abl, FGFR1, EGFR and c src respectively). PHA 665752 suppresses the hepatocyte growth factor induced cell proliferation and radioresistance in nasopharyngeal carcinoma cells. PHA 665752 reverses lung premalignancy induced by mutant K ras. PHA 665752 induced apoptosis of a lung adenocarcinoma cell line derived

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Description

1'E)-(2-methoxy-1

9-hexahydro-2H-pyrrolo[3

Smiles: NC(=N)SCC1=CC=C(CSC(N)=N)S1

two-way crossover

CAS Number: 2154342-56-8

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