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GSK2141795 Catalog No.:M8725-10 Vazquez-Carrera M

SKU: 88596172715

4.1
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GSK2141795 Catalog No.:M8725-10 Vazquez-Carrera MUprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is frequently

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Description

Vazquez-Carrera M

Kaspers GJ

Nagayasu A

5-fold and has an EC50 of 0

A Safety Study of LY2886721 Multiple Doses is performing in Healthy Subjects

GSK2141795 Catalog No.:M8725-10 Vazquez-Carrera MUprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is frequently

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