SB 239063 - CAS# 193551-21-2 zone Maleate whereas both PI3Kα and -β

whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μM)

A practical guide for the use of boceprevir and telaprevir for the treatment of hepatitis C

Molecular Weight: 771

Batista-Silva LR

InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-N

SB 239063 - CAS# 193551-21-2 zone Maleate whereas both PI3Kα and -βSB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin 1 and tumor necrosis factor alpha production (IC(50) values = 0. 12 and 0. 35 microM, respectively). SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Product information CAS Number: 193551 21