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Sudden discontinuation can cause: Adrenal crisis (medical emergency) Severe fatigue and body aches Low blood pressure Potentially life-threatening complications Infection Precautions While taking prednisone: Avoid close contact with people who have infections Report any signs of infection immediately: fever, sore throat, unusual symptoms Avoid live vaccines as your immune system cannot mount proper responses Be extra cautious about wound care and hygiene Regular Monitoring Required Your healthcare provider should monitor: Blood pressure regularly Blood sugar levels Bone density scans for long-term users Eye examinations for cataracts and glaucoma Growth in children on long-term therapy Contraindications Prednisone should not be used if you have: Active systemic fungal infections Known allergic reaction to prednisone or its components Certain live viral infections Drug Interactions and Precautions Prednisone interacts with numerous other medications, making it important to inform your healthcare provider about all medications youre taking

Smad2 and TGFR interactions, influencing gene transcription and cellular differentiation