(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg serum nitrate and (or) nitrite

serum nitrate and (or) nitrite level

02 mM) Ethanol 2 mg/mL (7

InChi: InChI=1S/C20H17FN2O3S/c1-14-12-16(15-8-4-2-5-9-15)13-18(19(14)21)20(24)22-23-27(25

is a potent and selective myeloperoxidase Inhibitor which is potential useful for the Treatment of Cardiovascular Diseases

It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand

(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg serum nitrate and (or) nitriteEtomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPAR.