L006235 - CAS# 294623-49-7 076 Indiplon is hydrolyzed by arylacetamide

Indiplon is hydrolyzed by arylacetamide deacetylase in human liver

and good oral bioavailability (F: 59%)

NSC636819 was used at 10 µM final concentration in vitro and in cellular assays

Chemical Name: 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride

Smiles: CC1=CC(=CC=N1)C1C=CC(CC(=O)NC2C=CC(=CC=2)C2=CN=CC=C2)=CC=1

L006235 - CAS# 294623-49-7 076 Indiplon is hydrolyzed by arylacetamideL006235, CAS No. 294623 49 7, also called L235, is a potent, reversible cathepsin K inhibitor (IC50 = 0. 25 nM) that displays > 4000 fold selectivity over cathepsins B, L and S. Product information CAS Number: 294623 49 7 Molecular Weight: 466. 60 Formula: C24H30N6O2S Synonym: L006235 L 006235 L235 L 235 L 006235 L 235 Chemical Name: N (1 ((cyanomethyl)carbamoyl)cyclohexyl) 4 (2 (4 methylpiperazin 1 yl)thiazol 4 yl)benzamide Smiles: