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KB-R7943 - CAS# 182004-65-5 Catalog No.:M6421-2 Molecular Weight: 510

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KB-R7943 - CAS# 182004-65-5 Catalog No.:M6421-2 Molecular Weight: 510KB R7943, CAS No. 182004 65 5, is a potent, selective inhibitor of the reverse mode of the Na+ Ca2+ exchanger (IC50 = 0. 7 M). KB R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB R7943 blocks opening of the mitochondrial permeability transition pore. KB R7943 restores endothelium dependent relaxation induced by advanced glycosylation end products in rat aorta. KB R7943 inhibits high glucose induced

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Description

Molecular Weight: 510

Chesler EJ

Biochemical and genetic studies showed that blockade of HDM2 and p21 abrogated P5091-induced cytotoxicity

In soft agar

or 300 mg/kg twice per week in subcutaneous xenografts of KARPAS-422 and Pfeiffer cells

KB-R7943 - CAS# 182004-65-5 Catalog No.:M6421-2 Molecular Weight: 510KB R7943, CAS No. 182004 65 5, is a potent, selective inhibitor of the reverse mode of the Na+ Ca2+ exchanger (IC50 = 0. 7 M). KB R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB R7943 blocks opening of the mitochondrial permeability transition pore. KB R7943 restores endothelium dependent relaxation induced by advanced glycosylation end products in rat aorta. KB R7943 inhibits high glucose induced

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