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GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg VU-0458298-2

GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg VU-0458298-2

Name: GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg VU-0458298-2
Brand: live-language.pl
SKU: 6713777898
Price: 85.00 USD
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SKU: 6713777898

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GSK2656157 - CAS# 1337532-29-2 Size:Solid 10 mg VU-0458298-2GSK2656157 is an ATP competitive inhibitor of PERK enzyme activity with an IC50 of 0. 9 nM. It is highly selective for PERK with IC50 values >100 nM against a panel of 300 kinases. GSK2656157 inhibits PERK activity in cells with an IC50 in the range of 10 30 nM as shown by inhibition of stress induced PERK autophosphorylation, eIF2 substrate phosphorylation, together with corresponding decreases in ATF4 and CHOP proteins in multiple cell lines. Oral

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Description

VU-0458298-2

InChi: InChI=1S/C13H10ClNO5S/c1-20-10-4-7-12(15(16)17)13(8-10)21(18

Go-6976 is found to abrogate S and G2 arrest

is a non-steroidal anti-inflammatory agent

17-triazaoctacyclo[12

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