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BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 0165 InChi: InChI=1S/C23H21N5O3S

BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 0165 InChi: InChI=1S/C23H21N5O3S

Name: BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 0165 InChi: InChI=1S/C23H21N5O3S
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BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 0165 InChi: InChI=1S/C23H21N5O3SBAY 87 2243, CAS No. 1227158 85 1, is a highly potent and selective inhibitor of hypoxia induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87 2243 mproves local tumor control after fractionated irradiation in a schedule dependent manner in head and neck human xenografts. BAY 87 2243 markedly decreased nuclear HIF 1 expression and pimonidazole hypoxic fraction already after 3 days of drug treatment.

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InChi: InChI=1S/C23H21N5O3S

and fitness of both human lamin A/C-depleted cells and HGPS-derived patient cells

6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1

KU 0059436

PARP-2 and other ARDT enzymes

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