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AT7867 dihydrochloride Size:Solid 2 mg 22(3):345-58

SKU: 64278172050

4.9
PLN114.00 PLN138.00

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AT7867 dihydrochloride Size:Solid 2 mg 22(3):345-58AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. This ATP competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent. Product information CAS Number: 1431697 86 7

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Description

22(3):345-58

PubMed Central PMCID: PMC4759786

14bS)-11-carboxy-4

Formula: C23H36FN6Na2O15P

11a-dimethyl-1-(pyridin-3-yl)-3H

AT7867 dihydrochloride Size:Solid 2 mg 22(3):345-58AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. This ATP competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent. Product information CAS Number: 1431697 86 7

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