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The antidepressant-like effects were proposed to result from direct activation of the AMPK signaling pathway, leading to enhanced serotonergic neurotransmission [66]

Regarding safety, the overall incidence of AEs was similar between the dose and placebo groups

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Rare but serious events encompass provocation or exacerbation of seizures in susceptible individuals and hypersensitivity reactions ranging from urticaria to anaphylaxis

A generic tracker might count calories, but GLP-1 weight loss is a different daily job: you need to see the trend line instead of panicking at one weigh-in, keep protein, water, and fiber visible when appetite is low, log the weekly shot, and notice how symptoms or hunger shift across the week