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PP1 890 Smiles: NC[C@@H]1CC[C@H](CC1)C(O)=O

SKU: 63016065078

4.2
EUR114.00 EUR158.00

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PP1 890 Smiles: NC[C@@H]1CC[C@H](CC1)C(O)=OPP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF beta1 induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF beta1 mediated cellular responses by direct and differential inhibition of type I and type II TGF beta receptors. PP1 was also found to potentiate tumor suppressive effect of connexin 32 gene in renal cancer cells. Product information CAS Number:

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Description

Smiles: NC[C@@H]1CC[C@H](CC1)C(O)=O

Smiles: CCOC(=O)C1C=CC(=CC=1)N1NC(=O)/C(=C/C2=CC=C(O2)[N+]([O-])=O)/C1=O

are less sensitive to S3I-201 at 100 μM or less

Co-administration of 20(S)-protopanaxatriol (g-PPT) and EGFR-TKI overcomes EGFR-TKI resistance by decreasing SCD1 induced lipid accumulation in non-small cell lung cancer

7R)-7-[(2R)-2-[(4-hydroxy-6-methylpyridin-3-yl)formamido]-2-(4-hydroxyphenyl)acetamido]-3-{[(1-methyl-1H-1

PP1 890 Smiles: NC[C@@H]1CC[C@H](CC1)C(O)=OPP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF beta1 induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF beta1 mediated cellular responses by direct and differential inhibition of type I and type II TGF beta receptors. PP1 was also found to potentiate tumor suppressive effect of connexin 32 gene in renal cancer cells. Product information CAS Number:

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