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1979-1984: Benaroya Institute, Seattle, WA

doi: 10.1016/j.rbmo.2020.09.019 306 ChinnathambiVBlessonCSVincentKLSaadeGRHankinsGDYallampalliCet al

(Dangshen) aqueous extract (DS) was identified as a core active metabolite and was directly related to the PI3K/Akt signaling pathway

& Crommelin, D

MIL-101 (Fe)@RSL3 NPs deliver iron ions and RSL3 to ccRCC cells, which generate large amounts of ROS through Fenton reactions, leading to the accumulation of LOX, and as GPX4 activity is inhibited by RSL3, this combination induces cell death by ferroptosis (171)