Go6893 - PKC Inhibitor. CAS# 133053-19-7 60432 Chemical Name: 4-acetamido-N-(2-aminophenyl)benzamide

Chemical Name: 4-acetamido-N-(2-aminophenyl)benzamide

CO-1686 potently and selectively inhibits growth of NSCLC cells expressing mutant EGFR and induces apoptosis

32)33)34-18-26-29-30-27(35-23-7-3-4-8-23)31(26)21-6-5-15-28-17-21/h5-6

evidenced by caspase and poly (ADP-ribose) polymerase cleavage

J Biol Chem

Go6893 - PKC Inhibitor. CAS# 133053-19-7 60432 Chemical Name: 4-acetamido-N-(2-aminophenyl)benzamideGo6983, CAS No. 133053 19 7, is a potent pan PKC inhibitor against for PKC, PKC, PKC, PKC and PKC with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively. It is inactive to PKC. Go6983 displays cardioprotective properties. It can reduce polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia reperfusion injury. It can also optimize nave human pluripotent stem cell growth and viability following nave cell derivation