Ro 61-8048 - CAS# 199666-03-0 Catalog No.:M8578-2 mice) shows improved efficacy (regression)

mice) shows improved efficacy (regression) in a 92

06% and 5%

Smiles: CC(C)(C)[C@H](NC(=O)CCOCCCOCCCOC1=CC2=NC=CC(OC3=CC=C(C=C3F)N(C(=O)C3(CC3)C(N)=O)C3C=CC(F)=CC=3)=C2C=C1OC)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1C

5-dihydro-1H-pyrazol-1-yl)nicotinate

2015 Dec 18:1-12

Ro 61-8048 - CAS# 199666-03-0 Catalog No.:M8578-2 mice) shows improved efficacy (regression)Ro61 8048 is a potent Kynurenine hydroxylase inhibitor (Ki = 4. 8 nM, IC50 = 37 nM). Ro 61 8048 improves dystonia in a genetic model of paroxysmal dyskinesia. Ro 61 8048 may be potentially useful for the treatment of dyskinesias. Ro 61 8048 could be a new avenue to reduce neuronal loss in brain ischemia. Product information CAS Number: 199666 03 0 Molecular Weight: 421. 45 Formula: C17H15N3O6S2 Synonym: Ro 61 8048 Chemical Name: 3,4 dimethoxy N [4 (3