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Tamoxifen citrate AC SGK3 degrader-1 1% in rats

SKU: 5912613351

4.8
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Tamoxifen citrate AC SGK3 degrader-1 1% in ratsTamoxifen, also known as ICI 46474, is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4 hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a selective estrogen receptor modulator. Tamoxifen is the usual endocrine (anti estrogen) therapy for hormone receptor positive breast cancer in pre menopausal women, and is also a standard in post menopausal

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Description

1% in rats

Solubility: DMSO : ≥ 46 mg/mL (106

14-trihydroxy-5-methyl-11

NVS-CRF-38

AZD2014 shows consistent exposure in rodents and a low turnover in human hepatocyte incubations

Tamoxifen citrate AC SGK3 degrader-1 1% in ratsTamoxifen, also known as ICI 46474, is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4 hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a selective estrogen receptor modulator. Tamoxifen is the usual endocrine (anti estrogen) therapy for hormone receptor positive breast cancer in pre menopausal women, and is also a standard in post menopausal

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