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Efonidipine Hydrochloride Size:Solid 10 mg Chemical Name: N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide

SKU: 58008885631

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Efonidipine Hydrochloride Size:Solid 10 mg Chemical Name: N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamideEfonidipine Hcl (NZ 105) is a dual T type and L type calcium channel blocker (CCB). IC50 value: Target: calcium channel blockerin vitro: Efonidipine and nifedipine, but not other examined CCBs, also increased the N(6), 2' O dibutyryladenosine 3',5' cyclic monophosphate (dbcAMP) induced StAR mRNA, which reflects the action of adrenocorticotropic hormone, and efonidipine and R( ) efonidipine enhanced the dbcAMP induced DHEA S production in NCI H295R

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Description

Chemical Name: N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide

Daisuke Irikura

Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ)

PHA-665752 potently inhibits the HGF-stimulated c-Met autophosphorylation with IC50 of 25-50 nM

InChi: InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2

Efonidipine Hydrochloride Size:Solid 10 mg Chemical Name: N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamideEfonidipine Hcl (NZ 105) is a dual T type and L type calcium channel blocker (CCB). IC50 value: Target: calcium channel blockerin vitro: Efonidipine and nifedipine, but not other examined CCBs, also increased the N(6), 2' O dibutyryladenosine 3',5' cyclic monophosphate (dbcAMP) induced StAR mRNA, which reflects the action of adrenocorticotropic hormone, and efonidipine and R( ) efonidipine enhanced the dbcAMP induced DHEA S production in NCI H295R

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