SD-208 - CAS# 627536-09-8 0003 23(19):5361-6

23(19):5361-6

Smiles: O[C@@H](CNC(=O)C1=CC(NC2COC2)=NC=N1)CN1CCC2=CC=CC=C2C1

3 nM) with reduced activity towards inhibition of ERK5 and TGFβR1 (IC50s = 810 and 1

(2012) AACR Annual Meeting: Chicago

CCR-19-3433

SD-208 - CAS# 627536-09-8 0003 23(19):5361-6SD 208, CAS No. 627536 09 8, also known as TGF RI Kinase Inhibitor V, is a novel protein kinase D inhibitor. SD 208 blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2 M cell cycle arrest. SD 208 reduces the development and progression of melanoma bone metastases. SD 208 inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo. Product information CAS Number: