PA-824 Catalog No.:M10553-10 It works by inhibiting photosynthesis

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PA-824 Catalog No.:M10553-10 It works by inhibiting photosynthesisPretomanid, aslo known as PA 824, a bioreductive drug. PA 824 has potent in vitro activity against Mycobacterium tuberculosis. PA 824 was tested in vitro against a broad panel of multidrug resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg ml). PA 824 showed significant activity at 2, 10, and 50 microg ml, similar to that of metronidazole, in a dose dependent manner. PA 824's good activity in in vivo

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