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PDGFR- Alpha Polyclonal Antibody, 100ul[BT-AP07017] Centrifugal Filter The basic (b) domain of

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PDGFR- Alpha Polyclonal Antibody, 100ul[BT-AP07017] Centrifugal Filter The basic (b) domain ofPDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides.

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Description

The basic (b) domain of bHLH transcription factors allows association with DNA

An N-terminal amphipathic helix

Male mice which lack TSSK6 encoding a highly similar protein are sterile and have morphologically abnormal sperm

NXPH4is a Protein Coding gene

Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H)| a disorder of the peripheral nervous system

PDGFR- Alpha Polyclonal Antibody, 100ul[BT-AP07017] Centrifugal Filter The basic (b) domain ofPDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides.

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