TH 1020 Size:2mg solid 5)1(6)7/h2-6

5)1(6)7/h2-6

Weinstein SF

This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs)

CAS Number: 1819366-84-1

14(13):1923-1934

TH 1020 Size:2mg solid 5)1(6)7/h2-6TH1020 is Toll like receptor (TLR) 5 Flagellin complex antagonist with IC50 of 0. 85 M. TH1020 competes with flagellin for TLR5 binding to inhibit the TLR5: flagellin interaction and subsequent downstream TNF secretion. Product information CAS Number: 1841460 82 9 Molecular Weight: 453. 54 Formula: C23H15N7S2 Chemical Name: 4 ((4 Benzyl 5 (pyridin4yl) 4H 1,2,4 triazol 3 yl)thio)pyrido[3',2': 4,5]thieno[3,2 d]pyrimidine Smiles: