Nordihydroguaiaretic acid - CAS# 500-38-9 481585 2019 May 17
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Nordihydroguaiaretic acid - CAS# 500-38-9 481585 2019 May 17Etrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model
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