Methylproamine - CAS# 188247-01-0 Size:Solid 10 mg Smiles: C[C@]12OC3=C(C1=O)C1C(C(O)=C3C)=C(O)C(=NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@H](C=CO2)OC)C2=NC3(CCN(CC(C)C)CC3)NC2=1 |c:22
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Methylproamine - CAS# 188247-01-0 Size:Solid 10 mg Smiles: C[C@]12OC3=C(C1=O)C1C(C(O)=C3C)=C(O)C(=NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@H](C=CO2)OC)C2=NC3(CCN(CC(C)C)CC3)NC2=1 |c:22Methylproamine is a DNA binding radioprotector which, on the basis of published pulse radiolysis studies, acts by repair of transient radiation induced oxidative species on DNA. IC50 Value: N ATarget: DNA binding radioprotectorin vitro: The extent of radioprotection at the clonogenic survival endpoint increased with methylproamine concentration up to a maximum dose modification factor (DMF) of 2. 0 at 10 M. At least 0. 1 fmole nucleus of
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