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NG25 ril (erbumine) At low doses

SKU: 42408282605

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NG25 ril (erbumine) At low dosesNG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38. NG 25 prevents TNF induced IKK phosphorylation and IB degradation in L929 cells. It inhibits secretion of IFN and IFN induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in

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Description

At low doses

2015 Nov 10

CAS Number: 6956-96-3

RS-127445 is a novel high affinity

PubMed PMID: 27306340

NG25 ril (erbumine) At low dosesNG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38. NG 25 prevents TNF induced IKK phosphorylation and IB degradation in L929 cells. It inhibits secretion of IFN and IFN induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in

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