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GDC046 Size:100 mg solid 3 μM and in a

SKU: 41610987796

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GDC046 Size:100 mg solid 3 μM and in aGDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4. 8 nM, 83. 8 nM, 27. 6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively. Product information CAS Number: 1258292 64 6 Molecular Weight: 350. 20 Formula: C16H13Cl2N3O2 Chemical Name: 2, 6 dichloro N (2 (cyclopropanecarboxamido)pyridin 4 yl)benzamide Smiles: O=C(NC1=CC(NC(=O)C2CC2)=NC=C1)C1C(Cl)=CC=CC=1Cl InChiKey: IAFNAEGXTKTGHN UHFFFAOYSA N

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Description

3 μM and in a non-competitive manner with respect to phosphatidylserine and ATP

Chemical Name: 7-chloro-3-(p-tolyl)-2H-benzo[b][1

2013 Feb 20

2016 Feb 12

The inhibitory effect of Staurosporine is statistically significant at around Wk 10 of tumor promotion

GDC046 Size:100 mg solid 3 μM and in aGDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4. 8 nM, 83. 8 nM, 27. 6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively. Product information CAS Number: 1258292 64 6 Molecular Weight: 350. 20 Formula: C16H13Cl2N3O2 Chemical Name: 2, 6 dichloro N (2 (cyclopropanecarboxamido)pyridin 4 yl)benzamide Smiles: O=C(NC1=CC(NC(=O)C2CC2)=NC=C1)C1C(Cl)=CC=CC=1Cl InChiKey: IAFNAEGXTKTGHN UHFFFAOYSA N

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