Derazantinib - CAS# 1234356-69-4 6049 It binds directly to the

It binds directly to the regulators of G-protein signaling domain of axin

thiophenecarboxamide IKK-2 inhibitors

Chemical Name: 2-((5-bromo-2-((3

Smiles: NS(=O)(=O)C1C=CC(=CC=1)NC1=CC(=O)C2=CC=CC=C2C1=O

InChi: InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2

Derazantinib - CAS# 1234356-69-4 6049 It binds directly to theDerazantinib, CAS No. 1234356 69 4, also known as ARQ 087, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR overexpressing tumor