EI1 K805 Formula: C25H24CaFNO4

Formula: C25H24CaFNO4

InChiKey: KVQOGDQTWWCZFX-UHFFFAOYSA-N

The expression of pFAK (Tyr397) is statistically significantly inhibited by Defactinib in a dose-dependent manner in all cell lines

RS-127445 is thus among the highest affinity

]pentadeca-1(11)

EI1 K805 Formula: C25H24CaFNO4EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Product information CAS Number: 1418308 27 6 Molecular Weight: 390. 48 Formula: C23H26N4O2 Synonym: Ezh2 inhibitor EI 1 EI 1 Chemical Name: 6 cyano N [(4,6 dimethyl 2 oxo 1,2 dihydropyridin 3 yl)methyl] 1 (pentan 3 yl) 1H indole 4 carboxamide Smiles: CC1C=C(C)NC(=O)C=1CNC(=O)C1=CC(=CC2=C1C=CN2C(CC)CC)C#N InChiKey: PFHDWRIVDDIFRP