HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 Liver fibrosis and hepatocyte apoptosis

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831

prevents the macropinocytic uptake of filoviral particles

AGC activity is also dramatically decreased in AT13148-administrated HGC27 tumors

GF 109203X inhibits collagen- and a-thrombin-induced platelet aggregation as well as collagen-triggered ATP secretion

3-30 μM) significantly reduces both inward and outward components of IClCa

HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 Liver fibrosis and hepatocyte apoptosisHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S