MLN 2480 - CAS# 1096708-71-2 4002 OTS514 Hydrochloride

OTS514 Hydrochloride

Chemical Name: N-(6-chloro-4-methyl-4-phenyl-2

InChi: InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9

Molecular Weight: 273

PubMed PMID: 24845199

MLN 2480 - CAS# 1096708-71-2 4002 OTS514 HydrochlorideTAK 580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan Raf kinase inhibitor. The Raf kinases (A Raf, B Raf and C Raf) are key regulators of cell proliferation and survival within the mitogen activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf. Product information CAS Number: 1096708 71 2 Molecular Weight: 506. 29 Formula: