Oligomycin A 060 as a therapeutic approach to

as a therapeutic approach to suppressing pancreatic cancer metastasis

thereby interfering with a key step in the autophagic process

is a specific inverse agonist of estrogen-related receptor γ (ERRγ) that inhibits pro-inflammatory cytokine-induced catabolic factors

about 3-fold selectivity over DDR2

100-150 mg/kg

Oligomycin A 060 as a therapeutic approach toOligomycin A, also known as MCH 32, is an inhibitor of ATP synthase. Oligomycin A inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production). The inhibition of ATP synthesis by oligomycin A will significantly reduce electron flow through the electron transport chain; however, electron flow is not stopped completely due to a process known as proton leak or