BMS-690514 Catalog No.:M10884-2 PF-3845 promotes neuronal survival

PF-3845 promotes neuronal survival

LPS-induced TNF-alpha production in mice

when comparing DM vs either ND or TR rats

small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity

is a functionalized IAP ligand for PROTACs

BMS-690514 Catalog No.:M10884-2 PF-3845 promotes neuronal survivalBMS 690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4, and vascular endothelial growth factor receptors (VEGFR) 1 3. BMS 690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo studies were conducted to characterize the pharmacokinetics and metabolism. Through integration of in vitro and in vivo pharmacokinetic data and antitumor efficacy in nude