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For analysis of circulating peptide hormones, data below the detection limit was considered as an outlier and omitted from data analysis

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Legerlotz, K., Jones, G

Informed consent was not required since the data only included register data

It also helps to see where epithalon sits within a structured longevity framework rather than as a standalone "fix." Frameworks that map peptides to the underlying driver of decline typically place epithalon in the cellular-aging and telomere category distinct from mitochondrial-metabolic candidates such as MOTS-c or immune-resilience compounds such as thymosin alpha-1