SB 203580 Catalog No.:M7716-2 Inhibition of p-LIMK with 1-50

Inhibition of p-LIMK with 1-50 μM of BMS-3 results in a dose-dependent decrease of p-Cofilin after 10 min incubation in capacitating conditions

1594:71-81

Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation

Small-molecule inhibitors of SETD8 with cellular activity

TAS0728 induces tumor regression in mouse xenograft models bearing HER2 signal–dependent tumors and exhibits a survival benefit without any evident toxicity in a peritoneal dissemination mouse model bearing HER2-driven cancer cells

SB 203580 Catalog No.:M7716-2 Inhibition of p-LIMK with 1-50SB203850 is a p38 MAPK inhibitor. SB203580 inhibits the phosphorylation of heat shock protein (HSP) 27 in response to IL 1, cellular stresses and bacterial endotoxin in vivo. SB203850 is useful for studying the physiological roles and targets of p38 MAPK and MAPKAP kinase 2. Product information CAS Number: 152121 47 6 Molecular Weight: 377. 43 Formula: C21H16FN3OS Synonym: Adezmapimod SB203850 SB 203850 Chemical Name: 4 (4 Fluorophenyl) 2 (4