SB 242235 - CAS# 193746-75-7 iglustat Hydrochloride BSJ-03-204 does not induce IKZF1/3

BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity

CAS Number: 29342-05-0

wetting agents or defoaming agents

is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay

Nafamostat mesilate (NM) prevents any significant release of neutrophil elastase

SB 242235 - CAS# 193746-75-7 iglustat Hydrochloride BSJ-03-204 does not induce IKZF1/3SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine mediated diseases such as autoimmune or inflammatory diseases. SB 242235 demonstrates generally favourable pharmacokinetic properties. Systemic plasma clearance was high in rat, but in the non rodent species SB 242235 demonstrated low to moderate clearance with plasma half lives > 4h. Oral bioavailability in each preclinical species was high. In