IC-87114 Catalog No.:M7740-2 Pressler ML

Pressler ML

Sacubitril (AHU-377) is converted by enzymatic cleavage of the ethyl ester into the active neprilysin inhibiting metabolite LBQ657

PROTAC FKBP Degrader-3 is a potent FKBP degrader

3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

SGC0946 was used at 1-5 µM final concentration in vitro and in cellular assays

IC-87114 Catalog No.:M7740-2 Pressler MLIC 87114 is a potent and ATP competitive PI3K p110 isoform selective inhibitor (IC50 = 60 nM). It Inhibits p110, p110 and p110 only at much higher concentrations. It does not inhibit other PIK related kinases such as ATM, ATR, DNA PK, and mTOR even at concentrations up to 100 M. Product information CAS Number: 371242 69 2 Molecular Weight: 397. 43 Formula: C22H19N7O Synonym: IC87114 IC 87114 Chemical Name: 2 ((6 amino 9H purin 9 yl)methyl) 5 methyl 3