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Silvestrol (aglycone) SMI-4 InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11

Silvestrol (aglycone) SMI-4 InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11

Name: Silvestrol (aglycone) SMI-4 InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11
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Silvestrol (aglycone) SMI-4 InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc LUC and tub LUC luciferase reporter protein translation, respectively. Anti cancer activity. Product information CAS Number: 960365 65 5 Molecular Weight: 478. 49 Formula: C27H26O8 Chemical Name: methyl (2S,3R,4R,5S,6R) 2,3,10 trihydroxy 12 methoxy 6 (4 methoxyphenyl) 5 phenyl 7 oxatricyclo[6. 4. 0. 0,]dodeca

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Description

InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11

6(27):24061-74

(2014) Proc Natl Acad Sci USA

CAS Number: 1005883-72-6

Shuhong Wu

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