WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 201 Exp Ther Med

Exp Ther Med

RG108 was used at 10-100 µM final concentration in various in vitro assays

Solubility: DMSO up to 40 mM

Smiles: CC1=CC=CC(=N1)C1=NN(C=C1C1=CC=NC2=CC=CC=C12)C(=S)NC1C=CC=CC=1

Stock Solution Storage: 0 - 4 oC for 1 month

WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 201 Exp Ther MedWS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat