GSK 2830371 decoxib 262(3):947-56

262(3):947-56

directly demonstrating the cardioprotective effect of PI3Kγ/δ inhibition

InChi: InChI=1S/C19H19N5O/c1-13-6-4-5-7-17(13)23-22-15-8-9-16(14(2)12-15)21-19(25)18-10-11-20-24(18)3/h4-12H

targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1)

InChi: InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7

GSK 2830371 decoxib 262(3):947-56GSK 2830371 is a WiP1 inhibitor. It inhibits cell growth and tumor growth in lymphoma and neuroblastoma models. Product information CAS Number: 1404456 53 6 Molecular Weight: 461. 02 Formula: C23H29ClN4O2S Chemical Name: (2S) 2 [(5 {[(5 chloro 2 methylpyridin 3 yl)amino]methyl}thiophen 2 yl)formamido] 3 cyclopentyl N cyclopropylpropanamide Smiles: CC1=NC=C(Cl)C=C1NCC1=CC=C(S1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1 InChiKey: IVDUVEGCMXCMSO FQEVSTJZSA N