ARN-509 - CAS# 956104-40-8 Size:Solid 2 mg Dembinski JL
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ARN-509 - CAS# 956104-40-8 Size:Solid 2 mg Dembinski JLApalutamide, also known as ARN 509 and JNJ 56021927 , is an androgen receptor antagonist with potential antineoplastic activity. ARN 509 binds to AR in target tissues thereby preventing androgen induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR responsive genes. This ultimately inhibits the expression of genes that regulate
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