BIO 091 PFI-1 induces dose-dependent reduction of

PFI-1 induces dose-dependent reduction of cell viability in T4302 CD133+ cells

15(3):265-76

and the chemo-proteomics approach demonstrated the superior selectivity of TMP269 relative to the other hydroxamate-substituted analogs via a chelating zinc-binding group

9)10/h2-12

Smiles: CO[C@H]1O[C@H](CO)[C@@H](OC(=O)NC2C=CC(=CC=2)C(=O)OCC)[C@H](OC(=O)NC2=CC3OCOC=3C=C2)[C@H]1OC(=O)NC1=CC2OCOC=2C=C1

BIO 091 PFI-1 induces dose-dependent reduction ofMLS 2052, aso known as BIO and GSK3 Inhibitor IX, is a cell permeable bis indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP competitive inhibitor of GSK3 (IC50 = 5 nM). Product information CAS Number: 667463 62 9 Molecular Weight: 356. 17 Formula: C16H10BrN3O2 Chemical Name: 6' bromo 3 nitroso 1H,1'H [2,3' biindol] 2' ol Smiles: OC1NC2=CC(Br)=CC=C2C=1C1NC2=CC=CC=C2C=1N=O InChiKey: SAQUSDSPQYQNBG UHFFFAOYSA N