KCNN3 (SK3) Polyclonal Antibody, 100ul Human Genome Knockout Libraries This gene encodes mitogen-activated protein

This gene encodes mitogen-activated protein kinase kinase kinase 14

closed conformation by an interaction between the kinase domain and the negative autoregulatory C-terminal coiled-coil region

Cloning of a comparable locus in mouse indicates that the encoded protein contains a discoidin domain and a carboxypeptidase domain

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression

interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation

KCNN3 (SK3) Polyclonal Antibody, 100ul Human Genome Knockout Libraries This gene encodes mitogen-activated proteinAction potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage independent calcium