TGR5 Polyclonal Antibody, 100ul Centrifugal Filter ADAMTS12 (ADAM metallopeptidase with thrombospondin

ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

E1A-like inhibitor of differentiation-1 (EID-1)

This subunit is a receptor for the antiepileptic drug

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

TGR5 Polyclonal Antibody, 100ul Centrifugal Filter ADAMTS12 (ADAM metallopeptidase with thrombospondinGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.